OR2M7 Gene
The OR2M7 gene encodes a particular olfactory receptor, a protein that reacts to specific molecules in the nose to trigger a signal in our perception of smell. OR2M7 encodes one of hundreds of different types of olfactory receptors in the nose. The sulfurous waste byproducts of consuming asparagusic acid, a chemical in asparagus, — and other chemicals similar to it — trigger the receptor encoded by OR2M7.
Alleles
People normally have two alleles per gene, one inherited from their mother and one inherited from their father.
Insensitive (Global)
This allele has been widespread globally for tens of thousands of years.
Sensitive (Global)
This allele has been widespread globally for tens of thousands of years.
Allele Pairs
It is the combination of a person's pair of gene alleles that influences traits.
| Predictable | Hardly Smells Asparagusic Acid Waste | |
| Allele Pair | People with this allele pair tend to be less sensitive to pungent odorants in asparagusic acid waste than those with one or two "Sensitive" alleles. | |
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| Predictable | Easily Smells Asparagusic Acid Waste | |
| Allele Pair | People with these allele pairs tend to be more sensitive to the pungent odorants in asparagusic acid waste than those with two "Insensitive" alleles. Their urine tends to be smelly to them after eating asparagus. | |
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Gene Details
The OR2M7 gene is located on chromosome 1 and encodes the protein named "Olfactory receptor 2M7", which influences the reported traits.
| Additional References | OR2M7 |
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| Wikipedia | OR2M7 |
| UniProt | Q8NG81 |
| U.S. National Center for Biotechnology Information | 391196 |
PubMed articles
Allele Definitions
| [0] | |
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| Sensitive |
A
T
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| Insensitive |
G
C
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| Show Minus Strand |
+
-
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| [0] | rs4481887 | dbSNP SNPedia |
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